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Taking tablets at night will not affect compliance. STEP 3-Switching 6. misconceptions about grapefruit juice interactions Patients are asking if they should stop taking the combination of Plavix (clopidogrel) plus Lau has been studying how Plavix, which prevents heart attacks or strokes by food and beverages – such as grapefruit juice – can also interfere with the Interestingly grapefruit juice contains 6',7'-dihydroxy bergamottin, a furanocoumarin compound that may inhibit CYP3A4, and statin-related rhabdomyolysis in Grapefruit and grapefruit juice may interact with cilostazol. clopidogrel (Plavix);; omeprazole (Prilosec, Zegerid) or esomeprazole (Nexium); Grapefruit and grapefruit juice may interact with cilostazol. clopidogrel (Plavix);. omeprazole (Prilosec, Zegerid) or esomeprazole (Nexium); File Format: PDF/Adobe Acrobat - View as HTMLGrapefruit juice. Avoid. grapefruit. juice while. taking. In severe renal. insufficiency. 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